Isomerization of BRCA1–BARD1 promotes replication fork protection

Nature, Published online: 03 July 2019; doi:10.1038/s41586-019-1363-4

BRCA1–BARD1 has a role in replication fork protection that is mediated by a mechanism of phosphorylation-targeted isomerization of BRCA1 and is independent of the canonical interaction between BRCA1 and PALB2.

 najlepsze tabletki odchudzające